APPROXIMATING REPRODUCTION NUMBERS: A GENERAL NUMERICAL METHOD FOR AGE-STRUCTURED MODELS


IF1 ablation prevents ATP synthase oligomerization, enhances mitochondrial ATP turnover and promotes an adenosine-mediated pro-inflammatory phenotype

Abstract ATPase Inhibitory Factor 1 (IF1) regulates the activity of mitochondrial ATP synthase.The expression of IF1 in differentiated human and mouse cells is highly variable.In intestinal cells, the overexpression of IF1 protects against colon inflammation.Herein, we have developed a conditional IF1-knockout mouse model in intestinal epithelium t

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